Lupus in dogs: Top Natural Remedies

September 27th, 2023 at 12:25 pm EST

Both our dogs and cats can get a variety of inflammatory diseases..

  • Allergies

  • Autoimmune Skin disease

  • Organ dsyfunction

  • Eye disease

  • Ear Infections

  • Cognitive Dysfunction

What is one supplement that can be VERY beneficial for this?

The medicinal ingredients found in the cannabis plant...cannabinoids.

If you have YET to get your dog/cat on one, here is one I suggest...

Dr Jones' ULTIMATE CBD Supplement for Dogs and Cats



Lupus – What is this?

Lupus is an immune-mediated disease stemming from the immune system reacting against your dog’s own DNA.

The name “lupus” stems from ANCIENT times when the disease was thought to have been caused by the bite of a wolf?

The immune system reacts to DNA and generates antibodies. These antibodies can then be deposited in a variety of areas, and that makes the diagnosis.

It can be the joint ( immune mediated joint disease), or the skin…hence Discoid Lupus.. .it then leads to an escalating cycle with other immunologic cells attracted and further inflammatory damage results.

Systemic lupus (SLE) involves this, Type III hypersensitivity reaction, affecting various organs.

Systemic Lupus Versus Discoid Lupus

When people use the term lupus, they are referring to systemic lupus, (SLE)

Discoid lupus is a form of lupus that is confined to the skin (Nose), and is substantially more benign. Discoid lupus, or DLE, is exclusively a canine disease and is limited to the nasal planum.

Conventional Therapy for Discoid Lupus

Avoid Strong Sunlight

Since this condition is made worse by the sun, it is important to avoid intense sunlight. Sunscreens have been advocated but it is important to realize that there are toxic ingredients in many human sunscreens and anything you apply to a dog’s nose will be licked off.


Tetracycline is an antibiotic with immunomodulating properties separate from its antibiotic properties. Niacinamide (also called nicotinamide) is a B vitamin supplement related to niacin (vitamin B3). The combination of these two medications has been found effective in 70% of dogs with DLE though it can take up to two months to see an effect. Treatment is given three times daily, which is relatively inconvenient for most people so alternatives have been sought. Doxycycline can be used twice a day and is frequently substituted for tetracycline.


Oral steroids are often used to get the condition under control relatively quickly (within a month) and can be used after that as the sole therapy after the lowest effective maintenance dose is determined. Side effects include panting, excessive thirst and urination, and increased appetite.

0.1% Tacrolimus (Protopic®)

This is a topical immunomodulator made for human use. It is very effective for use in DLE and does not cause problems if licked. Only small amounts of ointment are needed and the tube should last a long time which is good news since it is not inexpensive.

Alternative Options


Tattoo the nose as opposed to using sunscreen

Natural Steroids

Natural corticosteroid: Licorice Root Tincture at 1/2ml/20lbs twice daily for 14 days

Topical natural steroids

Topical: Licorice Root Tincture with Coconut Oil

2ml of licorice root, 2 tablespoons of coconut oil, apply 2-4 times/day

Fatty Acids

Omega 3 Fatty Acids can decrease level of inflammation and can be helpful. Dogs that has been diagnosed with an autoimmune disease should be on these. 500mg of Krill/30lbs daily.

Cannabidiol (CBD)

The cannabinoids, in particular CBD and those which target the CB2 receptors have been studied and shown to be beneficial in autoimmune disease. THC less so. They can be used orally and topically, and I would encourage anyone who has a dog with 'Collie Nose' to try CBD topically.

Heal Your Pet At Home!

Best Wishes,

Dr Andrew

P.S. The Endocannabinoid system (ECS) influences and modulates a variety of body processes including immune response, inflammation, pain, appetite, and mood. The CBD in our formula binds with receptors throughout your pet's body and provides many potential benefits, including modulating and supressing an overactive immune response.

Dr. Jones' Ultimate CBD Formula for Dogs and Cats by NuLeaf: Full Spectrum CBD supplement in 100% Organic Cold Pressed Hemp Oil.

Get your bottle here:

Dr Jones' ULTIMATE CBD for Dogs and Cats

DISCLAIMER: This information is for educational purposes only and is not intended to replace the advice of your own veterinarian. Dr Andrew Jones resigned from the College of Veterinarians of B.C. effective December 1 2010, meaning he cannot answer specific questions about your pet's medical issues or make specific medical recommendations for your pet.

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