Subject: SBIR Notes - December 2025

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SBIR Notes • December 2025
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Hi!

The Feds are open for business – but SBIR / STTR still stalled at the end of 2025!

Earlier this year, I was optimistic about SBIR/STTR re-authorization! I could not imagine that what seemed to be bi-partisan support of the program and the ongoing, and increasingly urgent, need to foster innovation in the U.S. would allow this key program to stall. However Congress has failed to pass any re-authorization legislation and efforts seem frustratingly stalled...

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As always if you need some help, we have an online course as well as personal coaching to help you put together an award-worthy proposal.
NEW OPPORTUNITIES

US Army

US CBD

DARPA

National Institutes of Health (NIH)
Note: The NIH registration process has changed.

National Science Foundation (Invests ~$200 million annually in startups).

CONFERENCES & SUMMITS



If you're interested in Nicole's help or want to know more about our VentureWrench SBIR coaching, just reply to this email and it will get to her right away!
ONGOING OPEN OPPORTUNITIES

US Chemical and Biological Defense Program
CBD254-005 Complex Geometries for Extended Wear Respirators Towards Regenerable Particulate Matter Protection
CBD254-006 Novel Sampling Tickets for Surface Enhanced Raman Spectroscopy (SERS) of Chemical and Biological (CB) Threat Materials
CBD254-007 Integrated Deployable Microsensors for Chemical Detection
CBD254-008 Far Forward Manufacturing of CBRN Sensors
CBD254-010 Shelf-Stable Nucleic Acid Synthesis Reagents for Field-Deployable Diagnostics
CBD254-011 OPEN TOPIC - Expeditionary Biologics-on-Demand (BOND)
CBD254-012 Microphysiological systems to Assess Pretreatment Immunogenicity and Efficacy (MAGPIE)

US DMEA
DMEA254-P001 RF Frontend Design (RFE) on Gallium Nitride on Silicon (GaN-on-Si) Open Topic

US DTRA
DTRA254-P005 Novel Technologies for CWMD and Related Threats - Open Topic

DARPA
HR0011SB20254-12 Assessing Security of Encrypted Messaging Applications (ASEMA)
HR0011SB20254-13 Pulsed High-power Laser Accelerators to Study radiation Hardening (PHLASH)
HR0011SB20254-15 Unbiased Behavioral Discovery Platforms




Department of Defense
Don't forget to check out my video course on SBIR:


It's full of practical, step-by-step instruction on how the SBIR/STTR REALLY  works!

Here's to Entrepreneurship!
Nicole and the VentureWrench Team

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