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| Make sure you put PMCB on your radar for tomorrow and get ready for what could be a monster day! |
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 Hot Stock to Watch |
Company: PharmaCyte Biotech, Inc. (OTCQB: PMCB)
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Last:
Price: 0.1277
Change (%): - 0.0088 (6.45)
Volume: 1,428,013 |
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PMCB recently reported that its partner, the University of Technology Sydney (UTS), has published a review article on cell and gene therapies for the treatment of diabetes. The publication, titled "The use of ß-cell transcription factors in engineering artificial ß cells from non-pancreatic tissue," which was authored by a member of PharmaCyte Biotech's Diabetes Consortium, Prof. Ann M. Simpson and her colleagues at UTS, appeared in the prestigious Nature publishing group scientific journal Gene Therapy. This review can be located by clicking here.
The article reports that cell and gene therapies have shown promise as a potential cure for Type 1 diabetes through the genetic engineering of non-pancreatic cells that makes them capable of regulating blood glucose levels by producing insulin on demand. Such genetic modification and augmentation of non-pancreatic cells has the ultimate goal of producing glucose-responsive "artificial" ß insulin-producing cells that mimic the function of pancreatic ß cells in non-diabetic individuals.
Using some of the technology discussed in the review article, Prof. Simpson and her colleagues have developed the Melligen cell line, a human non-pancreatic cell line that originated from liver cells that were genetically engineered to produce and store insulin and secrete it at levels in proportion to the levels of glucose (blood sugar) in the human body. The Melligen cell line is currently undergoing an initial evaluation for its utility in PharmaCyte Biotech's Cell-in-a-Box(R)-based treatment of diabetes, the first of a number of preclinical studies that will be performed by PharmaCyte Biotech's international Diabetes Consortium.
Kenneth L. Waggoner, Chief Executive Officer of PharmaCyte Biotech, said, "We are delighted by this important publication from one of the key members of our international Diabetes Consortium. Prof. Simpson is a world-renowned scientist in the field of diabetes and, as this publication shows, is at the forefront of research into finding a cure for this disease."
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