Subject: ONCX Initiates Important New Research with Cancer Research Leader MD Anderson

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ONCX Initiates Important New Research with Cancer Research Leader MD Anderson
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Company: Oncolix, Inc. (OTCQB: ONCX)


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Oncolix Sponsors Additional Research with MD Anderson Cancer Center

Research to Evaluate Prolanta™ for Uterine Cancer

HOUSTON, Jan. 31, 2018 (GLOBE NEWSWIRE) - Oncolix, Inc., (OTCQB:ONCX) announced today that the Company has sponsored additional research with MD Anderson Cancer Center. The research will evaluate ProlantaTM for the potential treatment of additional gynecological cancers, in particular uterine cancer. Previous research funded at the MD Anderson Cancer Center resulted in the discovery of the mechanism of action of ProlantaTM (autophagy) and preclinical evidence of efficacy in ovarian cancer.

“Because Prolanta has the potential to treat all gynecological cancers, it is only fitting that we expand our focus to uterine cancer,” said Michael T. Redman, chief executive officer of Oncolix. “Like ovarian cancer, more than 80% of uterine cancer cells overexpress prolactin receptors, which are the molecular target for ProlantaTM. Similarly, the unmet medical needs for uterine cancer are similar to ovarian cancer.”

Prolanta™ is being evaluated in an open-label dose escalation Phase 1 clinical trial in patients with advanced ovarian cancer. Patients are divided into three dosing groups, or cohorts. Each sequential cohort will evaluate a higher dose of Prolanta™. Patients will be evaluated over a 99-day period. Initial dosing for 28 days is followed by a two-week safety assessment period, and then continues for an additional 56 days if no toxicities are observed. The first cohort, treated with the lowest dose, was completed, and has shown no serious adverse events or dose-limiting toxicity. Earlier this January, the Company announced it is now recruiting the mid-dose patients for this trial. For more information about the Phase 1 clinical trial please visit: https://clinicaltrials.gov/ct2/show/NCT02534922?term=Prolanta&rank=1

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