Global CAR-T Cell Therapy Market – Market Size, Forecasts, Trials & Trends, 2024
Between 2017 and 2024, nine CAR-T products reached commercialization and this number is continuing to climb. Of these, six are U.S. FDA-approved CAR-T cell therapies, each of which has received approvals in other major healthcare markets as well. The six U.S. FDA approved products include: - Kymriah (tisagenlecleucel)
- Yescarta (axicabtagene ciloleucel)
- Tecartus (brexucabtagene autoleucel)
- Breyanzi (lisocabtagene maraleucel)
- Abecma (idecabtagene vicleucel)
- Carvykti (ciltacabtagene autoleucel)
In addition, two CAR-T therapies have received approval from the Chinese National Medical Products Administration, Relma-cel and Yuanruida, and one CAR-T cell therapy has received approval from the Indian Central Drugs Standard Control Organisation, NexCAR19.
Currently, all of the nine marketed CAR-T cell therapy products and nearly three-quarters (75%) of the ongoing clinical trials utilize an autologous treatment approach. Thus, the next frontier for CAR-T cell therapies will be the development of allogeneic CAR-T cell therapies. Solid tumor applications also attracting unprecedented investment.
This billion dollar CAR-T cell therapy market would not have been possible without the remarkable efficacy of the early CAR-T therapies in treating several types of blood cancers. Ranging from small start-ups to billion-dollar companies, CAR-T companies are now proliferating in all major healthcare markets worldwide.
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