Subject: Introducing CAIN's AMR Newsletter - August 15th, 2019

AMR eNews - August 15th, 2019
antimicrobial resistance
research & policy

Introducing our AMR eNews
Diseases that were once easily treated with antibiotics are now uncontrollably spreading across the globe. They are threatening the lives of millions, producing chronic health conditions, and costing the healthcare industry billions. 

The Canadian Anti-infective Innovation Network (CAIN) was formed in 2017 with the purpose of leveraging the many innovative approaches being developed across the country in an effort to solve the antimicrobial resistance (AMR) crisis. One of the most important ways we can do this is by increasing global awareness of AMR - and through our new AMR Newsletter, we hope to keep our public and partners informed with the latest news in both Canadian and international AMR research and policy. Our regular newsletter will also provide you with the best available learning resources in the field, as well as important information regarding upcoming AMR-related seminars and events taking place across the nation. We are confident that through education and action, we can overcome AMR together. 

Gerry Wright (McMaster University), Bob Hancock (University of British Columbia), & Don Sheppard (McGill University)
Canadian Anti-infective Innovation Network (CAIN)
global headlines

Development of new antibiotics encouraged with new pharmaceutical payment system

"We will take the lead but this is a global problem and we cannot succeed alone." - Matt Hancock, Britain's Health Secretary

GOV.UK: The NHS will test the world's first ‘subscription’ style payment model to incentivize pharmaceutical companies to develop new drugs for resistant infections.

Immune to drugs: antimicrobial resistance could kill 10 million a year

“Antibiotic resistance is one of the greatest public health challenges of our time.” - Centers for Disease Control and Prevention

FORBES: Bacteria, viruses and parasites are growing increasingly resistant to the drugs developed to combat them. In fact, antimicrobial resistance has surged into a public health nightmare around the world.

New report calls for urgent action to avert antimicrobial resistance crisis

"I urge all stakeholders to act on its recommendations and work urgently to protect our people and planet” - Ms. Amina Mohammed, United Nations Deputy Secretary-General

THE WHO: International organizations unite on critical recommendations to combat drug-resistant infections and prevent the staggering number of annual deaths.

canadian solutions

David Braley Centre for Antibiotic Discovery gives researchers a fighting chance against AMR

“This [centre] provides fresh resources to a team of researchers who are among the world’s leaders in their field.” - Paul O’Byrne, Dean and Vice-President of the Faculty of Health Sciences, McMaster University

MCMASTER NEWS: A forward-looking McMaster University donor is investing $7 million in a new research centre dedicated specifically to tackling the growing global threat of antimicrobial resistance.

McGill initiative tackles antibiotic resistance

"In 30 years, the number of deaths due to antibiotic resistant bugs will exceed that of cancer and heart disease.” - Dr. Don Sheppard, Professor of Molecular Mycology at McGill University

CITYNEWS: Antibiotic resistance is on the rise and a McGill initiative called MI4 is on the search for solutions.

Canada could lead the fight for life in a post-antibiotic world

"Canadian researchers have pioneered creative solutions: alternatives to antibiotics that block and inhibit resistance, innovative drug combinations that boost antibiotic activity and enhance host immunity to prevent infection." - Dr. Gerry Wright & Dr. Bob Hancock, co-founders of CAIN

THE NATIONAL POST (originally published in The Conversation): Diseases that once were tamed are roaring back, past the last line of our antibiotic defences. They threaten the lives of millions, but where is the public outcry?


The WHO (2019): Critically important antimicrobials for human medicine, 6th revision
The Canadian Anti-infective Innovation Network (CAIN) (2017): Drug Resistant Infections & Antimicrobial Resistance: A Pressing Threat to Modern Medicine
G20 (Prepared by OECD, WHO, FAO and OIE) (2017): Tackling Antimicrobial Resistance - Ensuring Sustainable R&D
Centers for Disease Control and Prevention (2017): Saving Lives By Taking A One Health Approach
Jim O'Neill (Commissioned by the UK Prime Minister) (2016): Tackling Drug-resistant Infections Globally: Final Report And Recommendations

Upcoming Events

NOVEMBER 14 / 15 

The 2019 Canada Gairdner Foundation / Ontario International Symposium: 
Global Innovations in Antimicrobial Resistance Research & Discovery

Drawing on the Canada Gairdner Awards’ history of recognizing the best in biomedical science, this symposia hosted by the Michael G. DeGroote Institute for Infectious Disease Research and David Braley Centre for Antibiotic Discovery will bring experts from across the world to present on the state of their field to an audience of students, faculty, and health and science professionals.

This two-day event is open the public, with registration opening in early Fall.

reports & publications

Outer membrane interaction kinetics of new polymyxin B analogs in Gram-negative bacilli

Phylogenetic reconciliation reveals the natural history of glycopeptide antibiotic biosynthesis and resistance

Discovery of a Novel DNA Gyrase-Targeting Antibiotic through the Chemical Perturbation of Streptomyces venezuelae Sporulation

Molecular mechanism of Aspergillus fumigatus biofilm disruption by fungal and bacterial glycoside hydrolases

High-Throughput Screening for Inhibitors of Wall Teichoic Acid Biosynthesis in Staphylococcus aureus.

who we are

The Canadian Anti-infective Innovation Network (CAIN) is a consortium of over 80 leaders, researchers, clinicians, and policymakers from Canadian universities, companies, governments, and not-for-profit organizations committed to addressing the global threat of antimicrobial resistance (AMR). CAIN members span human and animal health sectors, reflecting the fact that AMR is a One Health issue.

Stay up to date regarding the latest news in AMR research and policy.

The Canadian Anti-infective Innovation Network (CAIN) AMR eNews is proudly sponsored by the David Braley Centre for Antibiotic Discovery (DBCAD). For all communications, including any questions, comments, or suggestions that you may have regarding the AMR newsletter, please contact DBCAD Communications Coordinator Christy Groves at
The Canadian Anti-infective Innovation Network (CAIN)
University of British Columbia
Vancouver, BC

The David Braley Centre for Antibiotic Discovery
McMaster University
Hamilton, Ontario

The Michael G. DeGroote Institute for Infectious Disease Research
McMaster University
Hamilton, Ontario

McGill Interdisciplinary Initiative in Infection and Immunity (MI4)
McGill University

Montreal, Quebec

McMaster University, 1280 Main St W, Hamilton, Ontario L8S 4L8, Canada
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